[phenixbb] Twinned data with Phaser
pre at mrc-lmb.cam.ac.uk
Tue May 25 02:14:17 PDT 2021
I wonder whether our common metrics for assessing resolution are more optimistic for twinned data compared to untwinned - has anyone investigated that? Fewer weak reflections will reduce any sort of R-factor, but i’m not sure of its effect on CC(1/2)
There is always the question of what we mean by “the resolution of the data"
> On 24 May 2021, at 22:45, Thomas, Leonard M. <lmthomas at ou.edu> wrote:
> I have been working on a structure for a very long while. We have a number of data sets with the good ones mostly around the 3.1-3.2 A range. I do have a determination of the structure but would like to see if I can get the structure determined with a slightly higher resolution data set at around 2.7 A. Problem is the 2.7 data is twinned. Are there settings in Phaser to handle twinned data or is the twinning only handled during refinement?
> Thank you for any advice, outside of forgetting about the twinned data.
> Leonard Thomas, Ph.D.
> Macromolecular Crystallography Laboratory
> Oklahoma COBRE in Structural Biology
> Price Family Foundation Institute of Structural Biology
> University of Oklahoma
> Department of Chemistry and Biochemistry
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> lmthomas at ou.edu
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