[phenixbb] Postdoc Opening - Multi-Dataset Crystallography and Allostery - Keedy Lab, New York City

Daniel Keedy Daniel.Keedy at asrc.cuny.edu
Mon Jun 3 07:26:41 PDT 2019

The Daniel Keedy Lab at the CUNY Advanced Science Research Center in New York City has an available position for a Postdoctoral Researcher starting immediately.

The Keedy Lab aims to elucidate the conformational ensembles of proteins and to understand how they are shifted by perturbations, including mutations, protein:protein interactions, and ligands, to control function.  We are especially interested in how “hidden” conformational ensembles drive differences in allosteric regulatory mechanisms for protein tyrosine phosphatases (PTPs), which are under-studied but biologically critical.  To explore these questions, we are developing new multi-dataset approaches in X-ray crystallography that couple advances in automated data collection and multi-state modeling algorithms.  For more information, visit our newly designed lab website: www.keedylab.org<http://www.keedylab.org>

The ideal applicant should have a strong background in macromolecular X-ray crystallography, whether experimental, computational, or both.  Experience writing or contributing to scientific software is also preferred.  Candidates with other expertise in biophysics, computational biology, or related areas are also welcome to apply.

The CUNY Advanced Science Research Center is a new cutting-edge research institution located in upper Manhattan in New York City -- the "greatest city in the world".  The Structural Biology Initiative of the ASRC features seven tenure-track and research-track faculty members, pursuing diverse research problems using X-ray diffraction, cryo-EM, NMR, mass spectrometry, solution biophysics, and advanced microscopy.  The ASRC is immediately adjacent to the New York Structural Biology Center, a consortium of CUNY and eight other New York academic institutions with world-class facilities, and 70 miles from Brookhaven National Laboratory, featuring the newly constructed National Synchrotron Light Source II, now the brightest synchrotron light source in the United States.  The ASRC will also enjoy use of a new dedicated high-performance computing cluster starting this fall.

You can officially apply for the position here:


Feel free to contact Dr. Keedy directly at daniel.keedy at asrc.cuny.edu<mailto:daniel.keedy at asrc.cuny.edu> with your CV and a brief description of your interests if you would like to discuss possible projects.

Please pass this ad along to others who may be interested.

Come join us in NYC!

~Daniel Keedy

Daniel A. Keedy, Ph.D.
Assistant Professor
Structural Biology Initiative, CUNY Advanced Science Research Center
Department of Chemistry and Biochemistry, City College of New York
Biochemistry and Chemistry Ph.D. Programs, CUNY Graduate Center
www.keedylab.org<http://www.keedylab.org>   |  daniel.keedy at asrc.cuny.edu<mailto:daniel.keedy at asrc.cuny.edu>  |  212-413-3246

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