[phenixbb] questions related to Phenix refinement

Pavel Afonine pafonine at lbl.gov
Sun Jan 18 10:49:23 PST 2015

Dear Kay,

> Let me just make one remark: crystallography, although it resides on firm grounds, is complex enough that there are no simple rules for everything. It is oversimplification that has done a bad service to our science; just think of the "religious" Rsym cutoffs, in use until not long ago, that has caused people to discard a lot of valuable data. This is why I am against seemingly innocent rules of thumb like "the high-resolution cutoff should be done at X I/sigma or when the completeness falls below Y %" (and no, I'm not implying that you said this). There are better ways, but they are not as simplistic.

I can't agree more!


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