[phenixbb] Postdoctoral Fellow: Data Processing and Merging in Serial Crystallography

Kay Diederichs Kay.Diederichs at uni-konstanz.de
Mon May 19 07:38:22 PDT 2014

The Paul Scherrer Institute PSI is the largest research centre for
natural and engineering sciences within Switzerland. We perform
cutting-edge research in the fields of matter and materials, energy and
environment and human health. By performing fundamental and applied
research, we work on sustainable solutions for major challenges facing
society, science and economy. PSI is committed to the training of future
generations. Therefore about one quarter of our staff are post-docs,
post-graduates or apprentices. Altogether PSI employs 1900 people.

The Swiss Light Source (SLS) is one of the most advanced radiation
sources worldwide. The SLS Macromolecular Crystallography Group operates
two high performance undulator beamlines as well as a state-of-the-art
bending magnet beamline for protein crystallography. The group is
involved in several aspects of protein crystallography including the
development of advanced beamline instrumentation and crystallographic
methods, as well as structural biology projects in collaboration with
the Biomolecular Research Group at PSI and external partners.

In collaboration with Prof. Kay Diederichs at University of Konstanz, we
are looking for a

Postdoctoral Fellow: Data Processing and Merging in Serial Crystallography

Your tasks
* Serial crystallography with bright micro-focused X-ray beams from both
synchrotron and free electron laser sources has brought new
opportunities in micro- and nanocrystallography. At the same time,
obtaining best diffraction data from hundreds and thousands of crystals
presents unprecedented challenges. New statistics based method of
multi-crystal merging and analysis need to be developed and validated.
* Develop multi-crystal data analysis, processing and merging methods
for serial micro- and nanocrystallography at synchrotron radiation (SR)
and X-ray free electron laser (XFEL) sources
* Actively participate in serial crystallography experiments at both SR
and XFEL sources
* Implement an automated data merging pipeline at the SLS protein
crystallography beamlines

Your profile
You hold a PhD degree in (bio-)chemistry or physics and have several
years of experience in protein crystallography. Working knowledge for
data processing programs is a must. Experience in computer programming
would be a significant advantage. If you are a good team player with
good communication skills and sense of responsibility, this position
will offer a great opportunity for you to develop your research career
in an exciting and highly multidisciplinary environment.

For further information please contact Prof. Kay Diederichs, phone +49
7531 88 40 49 or Dr Meitian Wang, phone +41 56 310 41 75.

Please submit your application online (including list of publications
and addresses of referees) for the position as a Postdoctoral Fellow
(index no. 6112-00) to:

Paul Scherrer Institute, Human Resources Management, Miriam Zehnder,
5232 Villigen PSI, Switzerland

Kay Diederichs                http://strucbio.biologie.uni-konstanz.de
email: Kay.Diederichs at uni-konstanz.de    Tel +49 7531 88 4049 Fax 3183
Fachbereich Biologie, Universität Konstanz, Box M647, D-78457 Konstanz

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